Everything You Should Know About Herbal Medicine: The Ultimate 2023 Guide

By Dr. Gabriel Rodriguez

Herbal Medicine


Introduction
Herbal remedies have been used for centuries as natural solutions for common ailments and holistic healing. With growing interest in alternative medicine and botanical supplements, many are turning to herbalism to address issues like colds, allergies, stress, insomnia, digestive troubles, and more.

This complete beginner's guide will explore everything you need to know about herbal medicine, from the top medicinal herbs to proper usage and dosing. Read on to learn the benefits, precautions, and best practices for safely incorporating herbs and botanicals into your wellness routine.


A Brief History of Using Medicinal Herbs and Plants

Humans have relied on nature since ancient times to treat illness and injury. Herbal medicine refers to the use of plants, leaves, roots, flowers, seeds, stems and other botanical elements for their healing properties and medicinal benefits.

Almost every culture developed traditional herbal practices over centuries of use, experimentation, and shared knowledge. For example:

  • Ancient Chinese medicine used herbs like ginseng, licorice root, and rhubarb.
  • Ayurvedic medicine in India employed turmeric, neem, ginger, and ashgandha.
  • Native American traditions used echinacea, sage, black cohosh and juniper.
  • Ancient Greek and Roman doctors prescribed herbs like aloe vera, valerian, and thyme.

Today, modern herbalists carry on these traditions using plants for natural remedies as an alternative to conventional pharmaceuticals. Let's look closer at some of the top medicinal herbs gaining popularity.


Top Medicinal Herbs and Their Uses for Common Ailments

A vast array of herbs offers natural relief for various conditions. Here are some of the most common and effective medicinal herbs:

Echinacea for Colds, Flu, and Respiratory Infections

Echinacea is a top herbal remedy for boosting immunity during cold season. Multiple studies confirm Echinacea’s ability to shorten duration and reduce severity of upper respiratory infections, colds, flu and other viral illnesses. Its antiviral and anti-inflammatory effects make it an excellent choice for preventing and treating respiratory ailments.


Echinacea


Elderberry for Cold, Flu, and Congestion Relief

Elderberry demonstrates powerful antiviral activity against cold and influenza viruses. Supplements made from these berries can significantly reduce flu symptoms. Elderberry also enhances immune function and reduces nasal congestion and inflammation of the sinuses from colds.


Elderberry medicinal herb

Peppermint Oil for Upset Stomach, Nausea, and Digestive Issues

Peppermint is one of the most versatile medicinal herbs, used for GI problems like gas, bloating, nausea, vomiting, and indigestion. The menthol in peppermint provides a soothing, cooling sensation. It relaxes GI muscles to help relieve discomfort from digestion issues.


Peppermint Oil for Upset Stomach, Nausea, and Digestive Issues

Ginger to Ease Nausea, Upset Stomach, and Motion Sickness

For thousands of years, traditional cultures have used ginger as a natural remedy for nausea, vomiting, and other stomach complaints. Studies confirm ginger’s ability to reduce nausea related to motion sickness, pregnancy, and chemotherapy. Its anti-inflammatory properties also aid digestive distress.


Ginger to Ease Nausea

Turmeric as an Anti-Inflammatory and Joint Health Supplement

The active compound curcumin in turmeric exhibits powerful antioxidant and anti-inflammatory properties. Research shows turmeric can effectively reduce inflammation associated with arthritis, injuries, eczema, IBS, and other conditions. It may also support joint health and mobility.


Turmeric as an Anti-Inflammatory

Cayenne as a Digestion Aid and Pain Reliever

Cayenne pepper contains the active ingredient capsaicin, which has natural pain-relieving properties. Applied topically or taken orally, cayenne can temporarily relieve headaches, joint and nerve pain, and irritation from conditions like shingles. Cayenne may also boost metabolism and improve digestion.


Cayenne as a Digestion Aid


Herbal Allergy Relief from Butterbur, Nettle, and Other Botanicals

In addition to cold and flu relief, herbs can also counter the misery of seasonal allergies and hay fever:

  • Butterbur – This herb contains antihistamines that block allergy symptoms like sneezing, watery eyes, and runny nose. It may work as well as over-the-counter allergy meds with fewer side effects.

Butterbur

  • Nettle – Stinging nettle can reduce allergy symptoms and provide relief from hay fever. It contains histamine-inhibiting properties.

Nettle

  • Quercetin – This powerful antioxidant found in many fruits and vegetables may reduce inflammation and congestion caused by seasonal allergies.

Quercetin

  • Spirulina – Studies indicate this nutritious blue-green algae can significantly reduce nasal discharge and congestion from allergies and sinusitis.

Spirulina

When used in proper dosages, these herbal remedies can effectively combat allergy problems without the drowsiness and side effects of OTC medications. However, consult your doctor before use if taking other allergy meds or supplements.


Herbal Remedies for Anxiety, Stress and Insomnia

Many popular herbs offer natural sedative and calming properties to relieve anxiety, insomnia, and stress:

  • Kava – This herb acts as a natural tranquilizer by binding to brain receptors that reduce nervousness and induce relaxation.

Kava

  • Passionflower – Shown to be as effective as prescription medications for reducing anxiety symptoms without impairment or addiction potential.

Passionflower

  • Valerian – Well studied for improving sleep quality and duration, especially for those suffering from insomnia.

Valerian

  • Lavender – Aromatherapy using lavender essential oil demonstrates sedative effects that lower stress and anxiety levels.

Lavender Oil

  • Chamomile – A mild tranquilizer traditionally used for insomnia, general anxiety and nervous tension.

Chamomile Tea

  • Lemon Balm – The calming effects of lemon balm help induce sleep, improve sleep duration, and reduce anxiety-related insomnia.

Lemon Balm


However, caution is warranted as some herbs like kava and valerian can interact with other medications. It’s best to consult your doctor when considering herbal remedies for anxiety, stress or sleep issues.


Herbal Relief for Headaches and Migraines

For those plagued by migraines and headaches, several medicinal herbs may help reduce pain and frequency:

  • Feverfew – Used to prevent and treat migraine headaches. Thought to work by reducing inflammation.

Feverfew

  • Ginger – Can block pain-causing prostaglandins associated with migraine pain and headaches. Provides overall anti-inflammatory effect.
  • Cayenne – When used topically, capsaicin from cayenne may temporarily relieve headache pain by depleting pain neurotransmitters.
  • Willow Bark – Contains a compound similar to aspirin, exhibiting mild pain-relieving effects on headaches and joint pain.

Willow Bark


When applied at the first signs, these herbs may help nip headaches and migraines in the bud. Those prone to headaches should maintain an herbal first aid kit for acute pain relief.


Soothing Herbal Remedies for Skin Conditions

Herbal medicines also offer natural relief for various skin irritations and blemishes:

  • Calendula – Calendula creams and ointments can treat minor cuts, burns, rashes, eczema, and dermatitis. Has antimicrobial and anti-inflammatory activity when applied topically.

Calendula cream

  • Chamomile – Demonstrates anti-inflammatory, antimicrobial, and wound healing properties. Used in creams or ointments for eczema, burns, wounds, and hemorrhoids.
  • Green Tea – Applied topically, green tea exhibits antimicrobial activity that may be beneficial for treating acne and inflammatory skin conditions like rosacea.

Green Tea Cream

  • Witch Hazel – Has natural astringent properties. Used topically to help heal bruises, insect bites, inflamed skin, poison ivy, and hemorrhoids.

Witch Hazel Cream

  • Aloe Vera – Widely used as a topical treatment for burns, wounds, dry skin, rashes, and irritation. Promotes healing and soothes inflamed skin.

Aloe Vera Cream

When used appropriately, these herbal ingredients offer soothing, natural relief for common skin ailments that's gentle on sensitive skin.


Herbal Supplements for Improved Digestion and Nutrient Absorption

Many popular herbs can provide relief from digestive issues and improve gut health:

  • Peppermint – Relieves gas, bloating, cramping and other GI complaints through its antispasmodic effects on digestive muscles. Also improves bile flow.
  • Ginger – Treats nausea, vomiting, upset stomach, and supports healthy digestion. Has anti-inflammatory effects.
  • Fennel – Relieves heartburn, gas, bloating, colic and stomach pain. Fennel tea enhances healthy digestion.

Fennel Drink

  • Milk Thistle – Protects and repairs liver function. Improves digestion and reduces risk of stomach and intestinal cancers.

Milk Thistle drink

  • Probiotics – Provide healthy gut bacteria to regulate digestion and boost nutrient absorption. Widely used to treat diarrhea, IBS and Crohn’s disease.

Talk to your doctor before taking herbal supplements if you are already using medications for digestive issues like acid reflux, IBS, or ulcers.


Safety, Drug Interactions and Proper Dosing with Herbal Medicine

While herbal remedies offer many benefits, there are some safety considerations to keep in mind:

  • Possible Drug Interactions – Some herbs may interact with prescription medications. Always inform your doctor of any herbs or supplements you take.
  • Establishing Effective Doses – Herbal medicine dosing is complex. Follow label directions and consult a knowledgeable practitioner.
  • Contaminants – Poor quality herbs may contain toxic metals, fillers, or chemicals. Choose reputable brand supplements.
  • Long-Term Effects Unknown – The long-term safety of many herbs is still unknown. Use for short durations unless advised by an expert.

To reduce risks, work closely with a healthcare provider trained in herbal medicine when adding herbs and botanicals to your health regimen.


Choosing Quality Herbal Supplements – What to Look For

With the rise in herbal supplement use, many low-quality or adulterated products have entered the market. To choose effective, pure herbal remedies:

  • Purchase from Trusted Brands – Reputable manufacturers adhere to high quality control standards. Avoid generic supplements of unknown origin.
  • Check for Certifications – Look for seals from quality certifiers like U.S. Pharmacopeia and NSF International.
  • Read the Label Carefully – Ensure the product contains the listed herbs as the only medicinal ingredients without added fillers.
  • Research the Company – Check company reputation, manufacturing practices, and if they use independent laboratory testing.
  • Proper Storage is Key – Follow label storage directions. Light, heat and humidity degrade herbal compounds.

Consult your doctor before taking any new herbs or supplements, especially if you take other medications or have underlying health conditions. While many offer benefits, herbs can have powerful effects and may not be right for everyone.


Incorporating Herbs into a Holistic Lifestyle and Wellness Routine

To fully realize herbs’ benefits, incorporate them as part of an overall healthy lifestyle:

  • Maintain a Nutritious Diet – Eat a variety of vegetables, fruits, lean proteins and whole grains to get a range of protective plant compounds.
  • Stay Physically Active – Regular exercise boosts immunity, reduces inflammation, manages weight and prevents disease.
  • Reduce Stress – Practice yoga, meditation and mindfulness to lower stress hormones and anxiety. Getting quality sleep is also essential.
  • Support Detoxification – Take periodic breaks from caffeine, alcohol, refined sugars and processed foods that burden the body. Drink plenty of water.
  • Talk to a Professional – Work with a knowledgeable herbalist, naturopath or integrative doctor for guidance on herbs that suit your health goals and concerns.

While herbs offer targeted relief, cultivating overall wellbeing through nutrition, activity, stress management, and healthy routines enables herbal medicine to work optimally.


Putting It All Together – The Bottom Line on Herbal Medicine

Herbal medicine provides natural, plant-based remedies that offer relief for many common ailments and promote wellness:

  • When used appropriately, herbs like echinacea, elderberry, ginger and others can effectively treat issues like colds, allergies, headaches, anxiety, insomnia, digestion problems, and skin conditions.
  • Extensive research backs the benefits of many popular medicinal herbs for various uses. However, conclusive clinical evidence is still lacking for some herbs.
  • Quality and safety issues are concerns. Carefully research brands and choose reputable supplements confirmed to contain pure ingredients.
  • Proper usage and dosing is crucial. Use herbs under the guidance of knowledgeable practitioners. Avoid long-term use without professional oversight.
  • Herbalism works best as part of an overall healthy lifestyle routine that includes nutritious eating, staying active, reducing stress, and other wellness-promoting habits.

While herbal medicine shouldn’t replace professional medical care, many plants and herbs offer safe, natural relief when used responsibly. As research continues to uncover their health-enhancing properties, herbs will likely continue growing in popularity.


References and Recommended Resources:

  • National Center for Complementary and Integrative Health – Herbal Medicine Overview
  • University of Maryland Medical Center – Herbal Medicine Benefits and Risks
  • World Health Organization - WHO Monographs on Medicinal Plants
  • Natural Medicines Database - Professional Herbal Supplement Reviews
  • American Botanical Council – Resources on Botanical Medicine
  • American Herbalists Guild - Member Directory for Expert Herbalists




































The Promise and Facts About NAD+ as an Anti-Aging Supplement

NAD
Introduction
Aging is inevitable, but what if you could slow down or even reverse aspects of growing old? An emerging area of anti-aging research indicates it may be possible by boosting declining levels of a vital cellular coenzyme called NAD+. Supplements that increase NAD+ have shown promise in animal studies to counteract age-related decline. Ongoing human trials are investigating their long-term safety and effectiveness. This article explores the science behind using NAD+ precursors like nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) as anti-aging supplements. We’ll separate fact from fiction and discuss realistic expectations for their ability to turn back the clock.

NAD+, also known as nicotinamide adenine dinucleotide, has been growing in popularity as an anti-aging supplement. This coenzyme plays critical roles in energy production, DNA repair, gene expression, and other cellular processes that decline with age.

In recent years, research has revealed how NAD+ levels fall as we get older. This has prompted interest in using NAD+ boosters like nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) to potentially turn back the clock.

But does NAD+ really offer a “fountain of youth”? Can NAD+ precursors reverse aspects of aging as some headlines hype? Let’s take an evidence-based look at the science and unanswered questions around NAD+ supplements.


What Is NAD+ and Why Does It Decline?

NAD+ is a coenzyme found in all living cells. It plays a critical role as an electron carrier during cellular energy production and ATP generation.

NAD+ also activates proteins called sirtuins that regulate gene expression, DNA repair, circadian rhythms, inflammation, and metabolism. In addition, NAD+ is required for proper mitochondrial function.

During the normal aging process, NAD+ levels decline significantly. Research shows NAD+ concentrations decrease by up to 50% by middle age in humans and other mammals.

There are several reasons for this age-related NAD+ decline:

  • Decreased NAD+ biosynthesis - NAD+ is synthesized from precursors like nicotinamide obtained from food. NAD+ biosynthesis pathways become less efficient with age.
  • Increased NAD+ consumption - Cellular processes that require NAD+, like DNA repair and immune response, increase with age using up NAD+.
  • Mitochondrial dysfunction - Damaged mitochondria cannot recycle NAD+ effectively. This contributes to depletion over time.
  • Excessive CD38 activity - The protein CD38 consumes NAD+ but increases progressively after middle age.

The end result is substantially reduced NAD+ availability in older cells. This negatively impacts energy metabolism, DNA repair, gene expression, and other processes that NAD+ supports.


Early Research Revealed the Anti-Aging Potential of NAD+

Pioneering studies first revealed the influence of NAD+ on aging back in the 2000s.

Research showed boosting NAD+ levels in older mice partially reversed mitochondrial dysfunction and aspects of aging. Treated mice experienced benefits like improved cognition, increased endurance, and reduced DNA damage.

Other rodent studies found NAD+ supplementation extended average lifespan even when started late in life.

These animal models demonstrated the powerful anti-aging effects of maintaining youthful NAD+ levels. Human cells treated with NAD+ precursors also showed signs of rejuvenation and improved function.

This early evidence sparked a surge of interest in developing NAD+ boosting strategies. Researchers identified two naturally occurring precursors in particular that effectively elevate NAD+ levels when supplemented:

  • Nicotinamide riboside (NR) - A form of vitamin B3 that converts to NAD+ via the salvage pathway
  • Nicotinamide mononucleotide (NMN) - An intermediate molecule in NAD+ biosynthesis

Both NR and NMN demonstrated an ability to enhance NAD+ concentrations in rodent and human cells. This laid the groundwork for developing them into anti-aging supplements.


NAD Supplements


Clinical Research Investigates NAD+ Supplementation in Humans

Based on the compelling results from animal studies, clinical trials began investigating NAD+ precursor supplements in humans.

So far, research investigating NR and NMN supplementation in people is limited but appears promising:

  • Safety - Human trials report mild side effects so far like headaches and fatigue at higher doses. Long-term safety remains unknown.
  • NAD+ levels - Clinical studies show effective NAD+ increases in blood cells and tissues with supplementation. Levels return to baseline after stopping.
  • Mitochondrial health - Evidence indicates NR and NMN improve mitochondrial oxygen consumption and energy production.
  • Cognitive benefits - Some studies report cognitive gains like improved memory and focus from NAD+ boosters in older adults.
  • DNA repair - Clinical evidence shows NAD+ precursors may enhance DNA damage repair, similar to animal models.
  • Other benefits - Smaller trials show potential anti-inflammatory, neuroprotective, and metabolic effects.

Despite these encouraging preliminary findings, experts caution major gaps remain in our understanding of NAD+ supplement clinical effects and safety.


Ongoing Research Aims to Unlock the Full Potential of NAD+

The suggestive results from early human studies have fueled additional NAD+ research to better evaluate efficacy and optimal use:

  • Larger trials - Longer, bigger studies are underway measuring NAD+ effects on cognitive decline, immune function, metabolic health, inflammation, and muscle regeneration.
  • Dosing - Studies are working to identify ideal dosing and timing for NAD+ supplements to balance benefits and side effects.
  • Synergistic combinations - Scientists are exploring synergies from combining NAD+ boosters with exercise, fasting, and other interventions that raise NAD+.
  • Mechanisms - Research continues unraveling the complex molecular pathways through which NAD+ exerts its anti-aging effects.
  • Long-term effects - Longitudinal studies tracking outcomes over months and years will reveal enduring versus transient impacts of NAD+ supplementation.
  • Applications - Clinical trials are evaluating NAD+ therapy for specific age-related diseases like Alzheimer’s, heart disease, diabetes, and osteoarthritis.

Ongoing research aims to translate the robust anti-aging effects observed in animal models into proven human applications backed by rigorous evidence.


What Are Possible Side Effects or Risks of NAD+ Supplements?

NAD+ precursors like NR and NMN appear relatively safe at suggested supplement doses based on current data. However, there are some hypothetical concerns about long-term safety:

  • Unknown long-term effects - Human trials are limited in duration so far. Long-term impacts are still unknown.
  • Cancer risk - Some rodent data hints excessive NAD+ could stimulate growth of certain cancers. But data is mixed and unconfirmed.
  • DNA damage - There are concerns NAD+ could promote cancer by enhancing mutation-causing DNA damage repair. But this also remains speculative.
  • Pro-aging effects - Some research paradoxically links very high NAD+ to accelerated aging via overactivation of sirtuins and other pathways.
  • Liver toxicity - High doses of NR have shown potential liver damage in mouse studies. Human toxicity risks appear low but require more study.
  • Drug interactions - NAD+ boosters may interact with cholesterol drugs, blood pressure medications, chemotherapy, and immunosuppressants.

Overall, experts agree moderate NAD+ precursor doses appear safe based on current data. However, many advise caution until ongoing clinical trials clarify long-term effects and ideal dosing regimens.


Key Takeaways: Cautious Optimism for NAD+ Supplementation

  • Research shows boosting declining NAD+ levels may mimic the anti-aging benefits of exercise, fasting, and calorie restriction.
  • Early human trials show promise for NAD+ precursors like NR and NMN to improve biomarkers of aging.
  • However, data on long-term safety and ideal clinical use of NAD+ supplements remains limited.
  • Ongoing research aims to unlock the full therapeutic potential of NAD+ with rigorous clinical trials.
  • For now, many experts recommend cautious optimism and moderate use of NAD+ boosters until more evidence accrues.

In summary, current science offers reasons for excitement about NAD+ as a novel anti-aging strategy. But hype should be tempered until larger, longitudinal studies clarify long-term efficacy and optimal applications of NAD+ supplementation.


Frequently Asked Questions

What are common sources of NAD+?

NAD+ is found naturally in small amounts in foods like meat, fish, nuts, seeds, beans, avocados and whole grains. The precursors nicotinamide riboside and nicotinamide mononucleotide also occur in trace quantities in milk and other foods.

What is the recommended dosage for NAD+ supplements?

Clinical studies typically use doses of 250-500 mg per day of nicotinamide riboside or nicotinamide mononucleotide. Some manufacturers recommend starting with 100 mg. Experts emphasize beginning with lower doses.

How long does it take for NAD+ boosters to work?

Research shows oral supplements can effectively raise NAD+ levels within just a few hours. However, the timeline to achieve anti-aging effects is still under investigation.

Are there contraindications or precautions for NAD+ supplements?

Little is known about drug interactions and health precautions. As a precaution, it is advised to those with cancer or pregnancy to avoid NAD+ boosters until more safety data is available.

Can you get too much NAD+?

There is some concern very high NAD+ doses could potentially accelerate aging. Experts advise not exceeding supplement doses shown to be safe and effective in clinical trials.

Is it better to take NAD+ precursors or NAD+ directly?

The precursors NR and NMN effectively boost NAD+ levels when taken orally. Direct NAD+ compounds have shown limited absorption. Most supplements are NR or NMN-based.

The Bottom Line on NAD+ Supplements

Current science indicates NAD+ precursor supplements like NR show tangible promise to counter aspects of aging related to NAD+ decline. However, key questions remain unresolved around long-term safety, optimal dosing, timing, and clinical applications.

Larger ongoing trials will shed more light on these unknowns in coming years. In the meantime, experts generally recommend cautious, moderate use of NAD+ boosters. Maintaining a healthy lifestyle with exercise and good nutrition likely offers similar anti-aging effects.

While intriguing, the hype around NAD+ supplements outpace the current evidence. Those interested should temper expectations and carefully evaluate potential benefits versus unclear long-term risks. As future human studies report findings, the anti-aging prospects of NAD+ therapy will come into clearer focus.